Guidelines for optimizing design and analysis of clinical studies of nutrient effects.

نویسنده

  • Robert P Heaney
چکیده

Presented here is a system to standardize clinical studies of nutrient effects, using nutrient-specific physiological criteria. These guidelines are based mainly on analysis of the typical sigmoid curve of biological response to nutrients and are intended for design, interpretation, and pooling of studies of nutrient effects. Five rules have been articulated for individual studies of nutrients, and six for systematic reviews and/or meta-analyses.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Challenges in the Design, Conduct, Analysis, and Reporting of Randomized Clinical Trial Studies in Iran: A Qualitative Study

Background and Objectives: Randomized clinical trials are the gold standard for evaluating the effectiveness and safety of medical interventions. Some unpredictable challenges may affect the results of these studies. Therefore, the aim of this study was to identify the challenges of clinical trial studies in different stages including design, conduct, analysis, and reporting.   Methods: This ...

متن کامل

Optimizing Voyage Plan in way of Persian Gulf and Red Sea Using Meteorology and Oceanography Satellite Data

The weather forecast by satellite data is a good guideline for assessment of voyage planning route in order to have safe and economic voyage for shipping. ISO15016, "Guidelines for the assessment of speed and performance by analysis of speed trial data", has been developed by the working group ISO/TC 8/SC 9/WG 2. This paper presents the effects of wave speed & direction, wind speed and directio...

متن کامل

Determining and Optimizing Effective Factors in Laser Irradiation on Skin Tensional Strength using a Hybrid DOE and DEA Approach

Introduction: We investigated the characteristic of a suitable irradiation on skin's tensional strength using design of experiments (DOE). The experiments in this research are designed in two phases and data envelopment analysis (DEA) is used for performance measurement of each phase. Material and Methods: Samples were provided from pleura as surface tissue made of collagen and elastin fibers. ...

متن کامل

Development ofbioconsortia for optimizing nutrient supplementation through microbes for sustainable tobacco production

Increased interests in low-input agriculture in recent years has seen the growing developmentin the use of commercial biological inoculants to increase the mobilization of key nutrients suchas nitrogen (N), phosphorus (P) and potassium (K) to enhance their availability to crop plants.The objectives of this field experiment with tobacco were to determine i) reduced rates ofinorganic fertilizer c...

متن کامل

A review of Ramadan fasting and diabetes mellitus: Controversies regarding the effects of Ramadan fasting on diabetic patients

Although several studies have investigated the effects of Ramadan fasting on diabetic patients, the exact impacts on diabetes control have not been well elucidated yet. There are neither precise quantitative criteria nor clear guidelines regarding Ramadan fasting for diabetic patients. This review aimed to discuss the results of previous studies. The neglected points in performed studies should...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Nutrition reviews

دوره 72 1  شماره 

صفحات  -

تاریخ انتشار 2014